Amphibole is a common hydrous mineral in mafic calc-alkaline magmas. Due to its flexible crystal structure, amphibole covers a wide range of chemical composition, making it a crucial mineral phase for thermobarometry, oxybarometry, or diffusion chronometry. Up to date, only a limited amount of experimental studies focused on amphibole stability in basaltic to basaltic-andesitic systems, showing that amphibole crystallizes over a wide temperature (900-1100°C) and pressure range (0.2-1.0 GPa). Interestingly, melts from which these amphiboles crystallize contain at least 3-4 wt.% of H2O and 2 wt.% of Na2O. However, although these studies provide first insights, systematic investigations allowing us to predict accurately the effects of various parameters (e.g. pressure, temperature, bulk composition, or fO2) on amphibole crystallization are missing. The aim of our contribution is to explore experimentally and quantify the effects of these parameters on amphibole stability and chemistry. Equilibrium crystallization experiments were performed in internally heated pressure vessels (IHPV) at the Leibniz University Hannover at 200 and 400 MPa and temperatures between 900 and 1000°C employing varying initial bulk H2O contents (0.5-9 wt.%). Oxygen fugacity was buffered at conditions ranging from NNO to NNO+2.3. So far, two different starting compositions were used, namely a high-Mg basalt from the Adamello Batholith (Italy) and a magnesian basalt from the Cascades magmatic arc (USA) covering the typical compositional range of mafic arc magmas. Our preliminary results indicate that bulk system composition affects both amphibole stability (i.e. saturation temperatures), but also amphibole composition (e.g. Na2O, K2O, and TiO2 contents). Moreover, our experiments reveal that melt water contents represent a crucial parameter controlling amphibole crystallization. Ultimately, by combining our dataset with literature data, we formulated a preliminary empirical amphibole saturation model quantifying the crystallization dynamics of amphibole in calc-alkaline systems.